Wednesday, May 28, 2014

Promising target for treating leukemia

Courtesy – Institute for Research in Immunology and
Cancer of Université de Montréal
CANCER DIGEST РMay 28, 2014 РA group of researchers at the Institute for Research in Immunology and Cancer of Universit̩ de Montr̩al have identified a gene responsible for tumor progression in leukemia. The gene, known as Brg1, plays a key role in leukemia stem cells that are the root cause of the disease, and lead to treatment resistance and relapse. The researchers led by Julie Lessard say that when the gene is removed from the leukemic cells they no longer divide, thus effectively shutting down the disease progression. If drugs can be developed that block the drug, it might lead to effective treatment for leukemia and other cancers. Their study was published in the journal Blood.

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