Saturday, July 20, 2019

Broken heart syndrome linked to cancer

Image by Sakazaki used under Creative Commons license
CANCER DIGEST – July 20, 2019 – While the headlines grab the attention of the romantically inclined, there really is a medical condition affecting the heart resulting from traumatic emotional events called takotsubo cardiomyopathy.

The new international study led by Swiss researchers in the Journal of the American Heart Association, shows that a substantial number of patients with takotsubo syndrome (TTS) have an increased risk of cancer.
Identified 30 years ago by Japanese researchers, takotsubo cardiomyopathy is a weakening of the left ventricle, usually as the result of severe emotional or physical stress, such as a sudden illness, the loss of a loved one, a serious accident, or a natural disaster such as an earthquake. The left ventricle is the largest chamber of the heart and is responsible for pumping blood out to the rest of the body.

The syndrome is more common in women ages 58 to 75 years old and makes up as much as 5 percent of women who are evaluated for heart attack, as a result of chest pain, and abnormal electrocardiogram.

In the study researchers analyzed the cancer incidence of 1604 patients in the takotsubo registry, and found that 16.6 percent had both cancer and TTS, which is much higher than would be expected in the general population.

The researchers concluded that a substantial number of TTS patients show an association with malignancy and cancer screening among these patients should be considered.

Source: JAHA "Clinical features and outcomes of patients with malignancy and takotsubo syndrome: observations from the international takosubo registry," 17 Jul 2019 https://doi.org/10.1161/JAHA.118.010881

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