Wednesday, August 31, 2016

8 more cancers linked to excess weight

Copyright: Kurhan 
CANCER DIGEST – Aug. 31, 2016 – An international team of researchers has identified eight additional types of cancer linked to excess weight and obesity: stomach, liver, gall bladder, pancreas, ovary, meningioma (a type of brain tumor), thyroid cancer and the blood cancer multiple myeloma.

The findings are based on a review of more than 1,000 studies of excess weight and cancer risk analyzed by the World Health Organization’s International Agency for Cancer on Research (IARC), based in France.  The results of the analysis were published Aug. 25 in The New England Journal of Medicine.

“The burden of cancer due to being overweight or obese is more extensive than what has been assumed,” IARC chair Graham Colditz, MD, DrPH at Washington University School of Medicine in St. Louis said in a press release. "Many of the newly identified cancers linked to excess weight haven’t been on people’s radar screens as having a weight component.”

For most of the cancers on the newly expanded list, the researchers noted a positive dose-response relationship: the higher the body-mass index, or BMI, the greater the cancer risk.
The cancer risks associated with excess weight were similar for men and women and, when data were available, were consistent across geographic regions – North America, Europe, Asia and the Middle East.

There are many reasons why being overweight or obese can increase cancer risk, the researchers noted. Excess fat leads to an overproduction of estrogen, testosterone and insulin, and promotes inflammation, all of which can drive cancer growth.

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