Sunday, November 21, 2021

Surviving childhood cancer carries long-term health effects

Video credit – University College London

CANCER DIGEST – Nov. 19, 2021 – Children treated for cancer had five times as many visits to the doctor or hospital for cardiovascular disease as similar people who did not have cancer, a new study shows.

The study led by Dr. Alvina Lai of the University College London’s Institute of Health Informatics looked at the health records of 3,466 people diagnosed with cancer before age 25 and who survived at least 5 years and compared them to 13,517 people who did not have cancer. The results of their analysis were published in the journal The Lancet Regional Health - Europe on Nov. 14, 2021.

“Our study is the first to fully map out how surviving cancer early in life affects our health as we grow older," Dr. Lai said in a press release. "We believe it’s important for these long-term effects to be considered early on by families and their healthcare teams, so the benefits of a therapy can be weighed against any long-term risk."

The findings revealed that those treated with chemotherapy and radiotherapy had more than twice the number of hospital admissions overall by age 45 than those who only had surgery. Chemo/radiotherapy patients also had seven times as many visits to the doctor related to cardiovascular disease compared to those treated with surgery. They also had an increased risk of recurrent cancer and spreading, or metastatic cancer.

The data used was recorded between 1998 and 2020 and the cancer patients were matched for age, sex, and socioeconomic factors to patients without cancer. The researchers compared the two groups for 183 physical and mental conditions by the number of doctor or hospital encounters for each disease type. They also analyzed difference based on cancer type, treatment and dosage.

In addition to physical ailments, they also found a higher level of mental illness among cancer survivors compared to non-cancer patients.

Source: University College London press release

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