Saturday, February 17, 2018

Accuracy of tests for predicting breast cancer recurrence vary significantly

Image courtesy Queen Mary
University of London
CANCER DIGEST – Feb. 17, 2018 – Tests used to predict breast cancer recurrence vary significantly in accuracy according to the first side-by-side comparison of the four most common tests.

In a study published in the Feb. 15, 2018 journal JAMA Oncology researchers led by Ivana Sestak, PhD of the Centre for Cancer Prevention at Queen Mary University of London, compared the predictive performance of the four most widely used biomarker analysis tests: Oncotype DX, PAM50, Breast Cancer Index (BCI) and the EndoPredict (EPclin), which all work by looking at the levels of multiple genes related to breast cancer.

Saturday, February 10, 2018

Imaging-first strategy effective for prostate cancer


CANCER DIGEST – Feb. 9, 2018 – An advanced imaging technique is a cost-effective first test for the diagnosis of prostate cancer when followed by a combination imaging-guided biopsy say researchers.

The PROMIS study published in the January 2018 European Urology was designed to compare cost and effectiveness of three diagnostic strategies: transrectal ultrasound-guided biopsy (TRUSB), template prostate mapping biopsy (TPMB), and multiparametric magnetic resonance imaging (mpMRI) for the detection of clinically significant prostate cancer.

Friday, January 19, 2018

Another blood test for cancer shows promise


CANCER DIGEST – Jan. 19, 2018 – A team of researchers have developed another blood test for cancer, which if confirmed in clinical trials, could identify eight cancer types from a single blood draw.

The team at Johns Hopkins University of School of Medicine published its findings in the Jan. 18, 2018 journal Science. The test, called CancerSEEK simultaneously evaluates the levels of eight cancer proteins and the presence of cancer gene mutations from circulating DNA in the blood. Five of the cancers currently have no screening test.

Saturday, January 13, 2018

New test predicts age of onset of aggressive prostate cancer

CANCER DIGEST – Jan. 13, 2018 – A new test based on genomic research combined with population research is able to predict the age of onset of aggressive prostate cancer, researchers say.

The tool is based on searches of individual genomes, the entire set of genes that make up an individual, for small variations, called single-nucleotide polymorphisms or SNPs that occur more frequently in people with a particular disease compared to people without the disease.

Tuesday, December 26, 2017

Women with HPV-positive vulvar cancer have longer survival

Copyright: rocketclips / 123RF Stock Photo
CANCER DIGEST – Dec. 28, 2017 – An analysis of 18 studies of vulvar cancer involving 1,638 women showed longer survival for women who had been infected with the human papilloma virus (HPV) than women who did not have the infection, say researchers.

The study published online Nov. 16 ahead of the December 2017 issue of the International Journal of Cancer  was led by Dr. Christina Rasmussen of the Danish Cancer Society Research Center in Copenhagen, Denmark.