Video courtesy – CNIO |
CANCER DIGEST – July 28, 2014 – Transforming “bad” fat into “good” fat is currently one of the most researched processes of the body, thanks to the obesity epidemic. The bad fat is white and stored throughout the body, but in a process not fully understood, that stored fat is turned into good fat or brown fat that is burned for energy. While spurring that process is sought as a means to reduce obesity and diabetes, researchers in Spain
have discovered that the process may play a role in one-third of cancer deaths caused by cachexia (kuh-kek-see-uh), in which patients waste away in extreme thinness and weakness. In a study published in Cell Metabolism, Michele Petruzzelli and Erwin Wagner of the Spanish National Cancer Research Centre showed in mouse models of different cancers a consistent white fat to brown fat transformation was observed in all organ systems very early, before any sign of cachexia became apparent. Further research will be needed to learn how to inhibit cachexia and predict which cancer patients will develop it.
have discovered that the process may play a role in one-third of cancer deaths caused by cachexia (kuh-kek-see-uh), in which patients waste away in extreme thinness and weakness. In a study published in Cell Metabolism, Michele Petruzzelli and Erwin Wagner of the Spanish National Cancer Research Centre showed in mouse models of different cancers a consistent white fat to brown fat transformation was observed in all organ systems very early, before any sign of cachexia became apparent. Further research will be needed to learn how to inhibit cachexia and predict which cancer patients will develop it.
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